From ACC/AHA/ESC 2006 guidelines: JACC 2006;48:854-906
| High risk factors | Moderate risk factors | Weaker risk factors |
|---|---|---|
| Previous stroke, TIA, or embolism Mitral stenosis Prosthetic valve (INR >2.5) |
Age ≥ 75 Hypertension Heart failure LVEF < 35% Diabetes |
Female gender Age 65 - 74 Coronary artery disease Thyrotoxicosis |
| Risk category | Recommended therapy |
|---|---|
| No risk factors | Aspirin, 81 - 325 mg qd |
| 1 moderate risk factor | Aspirin, 81 - 325 mg qd - or - warfarin |
| >1 moderate risk factor or any high risk factor | warfarin |